Description

8-Bromo-7-(2-Ethoxyethyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, synthetically derived purine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the fields of oncology and neurology. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of adenosine receptor antagonists and other purine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Oncology Drug Discovery: Investigated for the development of novel kinase inhibitors and targeted cancer therapies.
• Neurological Disorder Research: Employed in creating compounds for potential use in treating conditions like Parkinson's disease and ischemia.
• Biochemical Tool Compound: Serves as a reference standard or probe in enzymatic assays and pharmacological studies.
• Custom Synthesis: Basis for the contract manufacturing of specialized, non-commercial purine derivatives for client-specific research programs.

Basic Information

Product Name	8-Bromo-7-(2-Ethoxyethyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	500198-78-7
Molecular Formula	C₁₀H₁₃BrN₄O₃
Molecular Weight	317.14 g/mol
Synonyms	8-Bromo-7-(2-ethoxyethyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 8-Bromo-7-(2-ethoxyethyl)-3-methylxanthine; 8-Bromo-7-(2-ethoxyethyl)-3-methyl-1H-purine-2,6(3H,7H)-dione; 8-Bromo-3-methyl-7-(2-ethoxyethyl)xanthine; 1H-Purine-2,6-dione, 8-bromo-7-(2-ethoxyethyl)-3-methyl-3,7-dihydro-; 500198-78-7; 8-Br-7-(2-EE)-3-Me-xanthine
EINECS	Contact for details

Quality Control

Our 8-Bromo-7-(2-Ethoxyethyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.