Description

1,3-Dioxolane-4-Carboxaldehyde,2-Ethyl-2-Phenyl-,(4R)-(9Ci) is a chiral, high-purity chemical intermediate characterized by its unique dioxolane-protected aldehyde functionality. This compound matters for its role as a critical building block in the synthesis of complex, stereochemically defined molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing active pharmaceutical ingredients (APIs) and other advanced organic materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in therapeutic areas requiring high stereochemical purity.
• Asymmetric Synthesis: Utilized in the construction of complex natural products and other bioactive molecules where the (4R) stereochemistry is essential.
• Ligand and Catalyst Development: Serves as a precursor for developing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials.
• Academic and Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxaldehyde,2-Ethyl-2-Phenyl-,(4R)-(9Ci)
CAS No.	500021-17-0
Molecular Formula	C₁₂H₁₄O₃
Molecular Weight	206.24 g/mol
Synonyms	(4R)-2-Ethyl-2-phenyl-1,3-dioxolane-4-carboxaldehyde; (R)-2-Ethyl-2-phenyl-1,3-dioxolane-4-carbaldehyde; 2-Ethyl-2-phenyl-1,3-dioxolane-4-carboxaldehyde, (4R)-; 500021-17-0; (R)-2-Phenyl-2-ethyl-1,3-dioxolane-4-carbaldehyde; (4R)-2-Ethyl-2-phenyl-[1,3]dioxolane-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxaldehyde,2-Ethyl-2-Phenyl-,(4R)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.