Description

1,3-Dioxolane-4-Carboxaldehyde, 2-Ethyl-2-Methyl-, (4R)- (9Ci) is a high-value, chiral building block and advanced pharmaceutical intermediate. Its defined stereochemistry and reactive aldehyde functionality make it a critical precursor for synthesizing complex, optically active molecules. This compound is essential for research and production in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Serves as a crucial starting material or intermediate in stereoselective organic synthesis, enabling the construction of molecules with high enantiomeric purity.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides and herbicides where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Development: Employed in the research and preparation of chiral ligands and organocatalysts for catalytic asymmetric transformations.
• Fine Chemical Production: Acts as a building block for manufacturing specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization within research laboratories.

Basic Information

Item	Details
Product Name	1,3-Dioxolane-4-Carboxaldehyde, 2-Ethyl-2-Methyl-, (4R)- (9Ci)
CAS No.	500021-09-0
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(4R)-2-Ethyl-2-methyl-1,3-dioxolane-4-carboxaldehyde; (R)-2-Ethyl-2-methyl-1,3-dioxolane-4-carbaldehyde; (4R)-2-Ethyl-2-methyl-[1,3]dioxolane-4-carbaldehyde; (R)-2-Ethyl-2-methyl-1,3-dioxolane-4-carboxaldehyde; 2-Ethyl-2-methyl-1,3-dioxolane-4-carboxaldehyde, (4R)-; (R)-(-)-2-Ethyl-2-methyl-1,3-dioxolane-4-carboxaldehyde; (4R)-2-Ethyl-2-methyl-1,3-dioxolane-4-carbaldehyde; (R)-2-Ethyl-2-methyl-1,3-dioxolane-4-carboxaldehyde (9CI)
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxaldehyde, 2-Ethyl-2-Methyl-, (4R)- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure high enantiomeric excess (ee) and chemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; allow the container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.