Description

1,3-Dioxolane-4-Carboxaldehyde, 2-(1-Methylethyl)-, (4R)- (9Ci) is a high-value, chiral aldehyde derivative of 1,3-dioxolane, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its defined stereochemistry at the 4-position makes it indispensable for the enantioselective construction of complex molecules, ensuring high optical purity in final products. This compound is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry is crucial for bioactivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the preparation of chiral ligands and organocatalysts used in stereoselective transformations.
• Fine Chemical & Flavor/Fragrance Intermediate: Employed in the synthesis of complex, high-value aroma chemicals and specialty fine chemicals requiring specific stereocenters.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, exploring new asymmetric synthesis routes and reaction mechanisms.

Basic Information

Item	Details
Product Name	1,3-Dioxolane-4-Carboxaldehyde, 2-(1-Methylethyl)-, (4R)- (9Ci)
CAS No.	500021-08-9
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(4R)-2-Isopropyl-1,3-dioxolane-4-carboxaldehyde; (R)-2-Isopropyl-1,3-dioxolane-4-carbaldehyde; (R)-2-Isopropanyl-1,3-dioxolane-4-carboxaldehyde; (4R)-2-(1-Methylethyl)-1,3-dioxolane-4-carboxaldehyde; (R)-2-(Propan-2-yl)-1,3-dioxolane-4-carbaldehyde; 2-Isopropyl-1,3-dioxolane-4-carboxaldehyde, (4R)-; Chiral 1,3-Dioxolane Aldehyde Derivative
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxaldehyde, 2-(1-Methylethyl)-, (4R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC/GC), to ensure high enantiomeric excess (ee) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C/59-77°F). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.