Description

1,3-Dioxolane-4-Carboxaldehyde, 2-Ethyl-2-Methyl-, (4S)- (9Ci) is a chiral, high-purity building block characterized by its dioxolane-protected aldehyde functionality. This compound is of significant value in asymmetric synthesis, serving as a key precursor for the introduction of stereochemically defined fragments into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and neurological therapeutic areas.
• Asymmetric Synthesis: Used as a versatile electrophile in stereoselective C-C bond-forming reactions, such as aldol additions and nucleophilic substitutions.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for the synthesis of chiral ligands used in transition metal catalysis.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and total synthesis projects.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxaldehyde, 2-Ethyl-2-Methyl-, (4S)- (9Ci)
CAS No.	500020-97-3
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(4S)-2-Ethyl-2-methyl-1,3-dioxolane-4-carboxaldehyde; (S)-2-Ethyl-2-methyl-1,3-dioxolane-4-carbaldehyde; (S)-2-Ethyl-2-methyl-[1,3]dioxolane-4-carbaldehyde; (S)-2-Ethyl-2-methyl-1,3-dioxolane-4-carboxaldehyde; (4S)-2-Ethyl-2-methyl-1,3-dioxolane-4-carbaldehyde; (S)-Dioxolane carboxaldehyde derivative; Chiral dioxolane aldehyde; (S)-EMDCA
EINECS	Contact for details

Quality Control

Our production of 1,3-Dioxolane-4-Carboxaldehyde, 2-Ethyl-2-Methyl-, (4S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), enantiomeric excess (typically >98% ee), and impurity profile is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or direct light should be avoided. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.