Description

Ethanone, 1-(4-Fluoro-3-Hydroxy-2,5-Cyclohexadien-1-Yl)- (9Ci) is a specialized fluorinated cyclohexadienone derivative, serving as a high-value synthetic intermediate. This compound is critical for research and development in advanced organic synthesis, where its unique structure enables the introduction of fluorine and ketone functionalities. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers with tailored optical or electronic properties.
• Academic & Industrial R&D: Employed in methodological chemistry research for studying fluorination reactions and cyclohexadienone chemistry.
• Ligand Synthesis: Useful for constructing complex ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Ethanone, 1-(4-Fluoro-3-Hydroxy-2,5-Cyclohexadien-1-Yl)- (9Ci)
CAS No.	500002-93-7
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	1-(4-Fluoro-3-hydroxy-2,5-cyclohexadien-1-yl)ethanone; 4-Fluoro-3-hydroxy-α,α,β,γ-cyclohexadien-1-acetophenone; 4'-Fluoro-3'-hydroxy-[1,1'-bi(cyclohexa-2,5-dien)]-4-one; Fluorohydroxy Cyclohexadienyl Ethanone; (4-Fluoro-3-hydroxy-2,5-cyclohexadien-1-yl) methyl ketone; 9CI Index Name: Ethanone, 1-(4-fluoro-3-hydroxy-2,5-cyclohexadien-1-yl)-
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-(4-Fluoro-3-Hydroxy-2,5-Cyclohexadien-1-Yl)- (9Ci) adheres to stringent quality management systems. Each batch is rigorously tested using advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specification parameters are provided with every shipment. We support cGMP and ISO 9001 compliant manufacturing for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening the primary container. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.