Description

(4R,14R,20S)-11β-Acetoxy-7α,20:18,20-Diepoxy-14,18-Dihydroxykaur-16-En-15-One is a highly functionalized kaurane diterpenoid derivative, valued for its complex stereochemistry and bioactive potential. This compound serves as a critical advanced intermediate in the synthesis of novel pharmaceutical agents and natural product analogs. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the exploration of new therapeutic pathways.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in oncology and metabolic disease research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop novel analogs with improved efficacy and selectivity.
• Natural Product Synthesis: Serves as a precursor in the semi-synthesis or total synthesis of complex diterpenoid natural products.
• Biochemical Research: Employed as a reference standard or probe compound in enzymatic and receptor binding assays.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing reaction conditions for pilot-scale production.

Basic Information

Product Name	(4R,14R,20S)-11β-Acetoxy-7α,20:18,20-Diepoxy-14,18-Dihydroxykaur-16-En-15-One
CAS No.	59860-00-3
Molecular Formula	C22H28O7
Molecular Weight	404.45 g/mol
Synonyms	11β-Acetoxy-7α,20:18,20-diepoxy-14,18-dihydroxykaur-16-en-15-one; 7α,20:18,20-Diepoxy-11β-acetoxy-14,18-dihydroxykaur-16-en-15-one; Kaur-16-en-15-one, 11-(acetyloxy)-7,20:18,20-diepoxy-14,18-dihydroxy-, (4R,7α,11β,14R,20S)-; 59860-00-3; (4R,14R,20S)-11β-Acetoxy-7α,20:18,20-diepoxy-14,18-dihydroxykaur-16-en-15-one
EINECS	Contact for details

Quality Control

Our high-purity diterpenoid intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation, to ensure identity, strength, and composition. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.