Description

1-Propionylpyrrolidine-2-Carboxylic Acid is a high-purity, versatile organic building block and chiral intermediate of significant interest in advanced chemical synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemistry and functional group compatibility.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptidomimetic Chemistry: Serves as a constrained proline analog for designing and synthesizing peptide mimics with enhanced stability and bioavailability.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to introduce chiral centers into complex molecules.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in stereoselective transformations.
• Academic and R&D Laboratories: Used in methodological studies and the exploration of new synthetic pathways in organic chemistry.

Basic Information

Product Name	1-Propionylpyrrolidine-2-Carboxylic Acid
CAS No.	59785-64-7
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	N-Propionyl-L-proline; (S)-1-Propionylpyrrolidine-2-carboxylic acid; L-Proline, N-propionyl-; 2-Pyrrolidinecarboxylic acid, 1-(1-oxopropyl)-, (S)-; N-Propionylproline; Propionylproline; 1-Propionyl-2-carboxypyrrolidine
EINECS	Contact for details

Quality Control

Our 1-Propionylpyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.