Description

(14R)-5,10,14,16-Tetrahydroxygrayanotoxane-3,6-Dione is a specialized grayanotoxin derivative, a class of diterpenoid compounds known for their complex polycyclic structures and significant biological activity. This high-purity compound is critical for advanced research and development in pharmacology and natural product chemistry. It serves as a valuable reference standard and synthetic intermediate for scientists in pharmaceutical, agrochemical, and academic institutions exploring novel bioactive molecules.

Application

• Pharmaceutical Research: Used as a key reference standard and intermediate in the study of sodium channel modulators and neuroactive compounds.
• Natural Product Synthesis: Serves as a sophisticated building block for the total synthesis or semi-synthesis of complex grayanotoxin analogs.
• Toxicology Studies: Employed as an analytical standard in the identification and quantification of grayanotoxins in food safety and forensic analysis.
• Biochemical Assay Development: Utilized in high-throughput screening and assay development to discover new therapeutic agents targeting ion channels.
• Academic Research: A crucial compound for university and institutional research into the structure-activity relationships of diterpenoids.
• Agrochemical Discovery: Investigated as a lead compound for the development of novel, naturally-inspired bioactive agents.

Basic Information

Product Name	(14R)-5,10,14,16-Tetrahydroxygrayanotoxane-3,6-Dione
CAS No.	59740-27-1
Molecular Formula	C20H30O7
Molecular Weight	382.45 g/mol
Synonyms	Grayanotoxin XIX; (14R)-Grayanotoxane-3,6,5,10,14,16-hexaone; 5,10,14,16-Tetrahydroxygrayanotoxane-3,6-dione; Grayanotoxin derivative; Andromedotoxin analog; Rhodojaponin related compound; Acetylandromedol precursor; Ericaceous toxin intermediate
EINECS	Contact for details

Quality Control

Every batch of (14R)-5,10,14,16-Tetrahydroxygrayanotoxane-3,6-Dione is manufactured under strict quality management systems. The product undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the exacting standards required for research applications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, the container should be kept in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.