Description

(Rs)-1-[3-(Trifluoromethyl)Phenyl]Ethylamine is a chiral amine building block of significant importance in advanced organic synthesis. Its core value lies in the combination of a chiral center and a robust, electron-withdrawing trifluoromethyl group, which is highly sought after for modulating the physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where stereochemistry and fluorine incorporation are critical for efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and metabolic disease drug candidates.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and advanced organic materials.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in research due to its amine functionality and fluorine tags.

Basic Information

Product Name	(Rs)-1-[3-(Trifluoromethyl)Phenyl]Ethylamine
CAS No.	59382-36-4
Molecular Formula	C9H10F3N
Molecular Weight	189.18 g/mol
Synonyms	(R,S)-1-[3-(Trifluoromethyl)phenyl]ethanamine; α-Methyl-3-(trifluoromethyl)benzeneethanamine; 1-(3-Trifluoromethylphenyl)ethylamine; (RS)-1-(3-Trifluoromethylphenyl)ethylamine; (±)-1-[3-(Trifluoromethyl)phenyl]ethylamine; 3-(Trifluoromethyl)phenethylamine, α-methyl-; (RS)-α-Methyl-3-(trifluoromethyl)phenethylamine
EINECS	Contact for details

Quality Control

Our (Rs)-1-[3-(Trifluoromethyl)Phenyl]Ethylamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity determination, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee consistent quality, identity, and purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99:1 Rs:Sr (or as specified)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.