Description

5,12-Naphthacenedione, 8-Acetyl-7,8,9,10-Tetrahydro-6,8,10,11-Tetrahydroxy-1-Methoxy-, (8S,10R)- is a complex, stereochemically defined tetrahydroxynaphthacenedione derivative. This compound matters as a sophisticated chemical intermediate, valued for its specific chiral configuration and functional group array, which are critical for synthesizing advanced molecules. It is primarily needed by research institutions and pharmaceutical development teams working on novel bioactive compounds, including potential antibiotics and anticancer agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel tetracycline-class antibiotics and other complex pharmacologically active molecules.
• Chemical Research & Development: Used in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies for polycyclic quinones.
• Biochemical Probe Development: Acts as a precursor for creating specialized probes to study enzymatic processes and cellular interactions due to its redox-active quinone moiety.
• Advanced Material Synthesis: Investigated for potential use in creating organic semiconductors or photoactive materials, leveraging its conjugated system.

Basic Information

Product Name	5,12-Naphthacenedione, 8-Acetyl-7,8,9,10-Tetrahydro-6,8,10,11-Tetrahydroxy-1-Methoxy-, (8S,10R)-
CAS No.	59325-98-3
Molecular Formula	C₂₁H₂₀O₉
Molecular Weight	416.38 g/mol
Synonyms	(8S,10R)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione; 8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione (8S,10R)-; 1-Methoxy-8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-5,12-naphthacenedione; AAT; AATD; Tetrahydroxymethoxynaphthacenedione derivative; Chiral naphthacenedione intermediate
EINECS	Contact for details

Quality Control

Our 5,12-Naphthacenedione derivative is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC and structural confirmation by NMR and MS, to ensure high chemical and isomeric purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (8S,10R)-isomer
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.