Description

(14R)-Grayanotox-10(20)-Ene-3β,5,6β,14,16-Pentol 6-Acetate is a specific, acetylated derivative of the grayanotoxin diterpene family, known for its complex polyhydroxylated structure. This high-purity compound is of significant interest for advanced research and development in pharmacology and toxicology. It serves as a critical reference standard and a key synthetic intermediate for scientists and manufacturers in the pharmaceutical, agrochemical, and life science sectors.

Application

• Pharmacological Research: Acts as a precise reference standard and a key intermediate in the study of sodium channel modulation and neurotoxicology.
• Toxicology Studies: Used for calibrating analytical methods and conducting safety assessments related to grayanotoxin exposure.
• Natural Product Synthesis: Serves as a sophisticated building block for the semi-synthesis of novel grayanotoxin analogs and derivatives.
• Analytical Chemistry: Employed as a high-purity calibrant in HPLC, LC-MS, and NMR for method development and validation.
• Biochemical Assays: Utilized in in vitro studies to investigate specific receptor interactions and cellular signaling pathways.
• Academic & Institutional Research: Supports fundamental research in organic chemistry, medicinal chemistry, and plant biochemistry.

Basic Information

Product Name	(14R)-Grayanotox-10(20)-Ene-3β,5,6β,14,16-Pentol 6-Acetate
CAS No.	59236-87-2
Molecular Formula	C22H34O7
Molecular Weight	410.50 g/mol
Synonyms	Grayanotoxin III 6-Acetate; Grayanotoxin III Monoacetate; 6-O-Acetylgrayanotoxin III; (3β,5α,6β,14R)-Grayanotaxane-3,5,6,10,14,16-hexol 6-Acetate; 6-Acetoxygrayanotoxin III; Acetylandromedol; 14-Hydroxygrayanotoxin III 6-acetate; Andromedotoxin derivative
EINECS	Contact for details

Quality Control

Our (14R)-Grayanotox-10(20)-Ene-3β,5,6β,14,16-Pentol 6-Acetate is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability, consistency, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, storage at 2-8°C is recommended. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.