Description

3-Amino-4-Cyano-1-Phenyl-1H-Pyrrole-2-Carboxylic Acid Ethyl Ester is a high-purity pyrrole derivative, a crucial heterocyclic building block in advanced organic synthesis. Its molecular architecture, featuring amino, cyano, and ester functionalities, makes it an indispensable intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active compounds and dyes.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and other bioactive heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyrrole core contributes to biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or emissive layer components in OLED device fabrication.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized dyes, pigments, and optical brighteners due to its conjugated system.
• Academic & Industrial Research: A valuable reagent in method development, catalysis studies, and the synthesis of complex natural product analogs.
• Coordination Chemistry: Can function as a ligand for metal complexes in catalytic and material science applications.

Basic Information

Item	Detail
Product Name	3-Amino-4-Cyano-1-Phenyl-1H-Pyrrole-2-Carboxylic Acid Ethyl Ester
CAS No.	59021-51-1
Molecular Formula	C14H13N3O2
Molecular Weight	255.27 g/mol
Synonyms	Ethyl 3-Amino-4-cyano-1-phenyl-1H-pyrrole-2-carboxylate; 1H-Pyrrole-2-carboxylic acid, 3-amino-4-cyano-1-phenyl-, ethyl ester; 3-Amino-1-phenyl-1H-pyrrole-2,4-dicarbonitrile, 2-ethoxycarbonyl derivative; Ethyl 3-amino-1-phenyl-1H-pyrrole-2,4-dicarboxylate nitrile; 59021-51-1; 1-Phenyl-3-amino-4-cyano-pyrrole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Cyano-1-Phenyl-1H-Pyrrole-2-Carboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.