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3,5,6-Trichloro-2-Pyridinol Glucuronide CAS NO 58997-12-9


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CAS No.:58997-12-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3,5,6-Trichloro-2-Pyridinol Glucuronide is a key conjugated metabolite of the organophosphate insecticide chlorpyrifos. This compound is critical for environmental monitoring, toxicological research, and regulatory compliance, serving as a definitive biomarker for exposure assessment. It is primarily utilized by analytical laboratories, agrochemical manufacturers, and research institutions focused on pesticide metabolism, human biomonitoring, and ecological safety studies.

Application

  • Biomarker Reference Standard: Serves as a certified reference material (CRM) for the accurate quantification of chlorpyrifos exposure in human and animal urine samples for biomonitoring programs.
  • Toxicology & Metabolism Studies: Essential for investigating the metabolic pathways, pharmacokinetics, and excretion profiles of chlorpyrifos in preclinical and environmental toxicology research.
  • Environmental Analysis: Used as an analytical standard in LC-MS/MS and HPLC methods to detect and quantify pesticide residues in water, soil, and agricultural runoff.
  • Regulatory Compliance & Method Development: Supports the development and validation of analytical methods required for regulatory submissions to agencies like the EPA and EFSA.
  • Diagnostic Kit Manufacturing: Employed in the production and calibration of immunoassay kits designed for rapid screening of organophosphate pesticide metabolites.
  • Academic Research: A vital reagent for universities and research institutes studying the environmental fate and human health impacts of organophosphate pesticides.

Basic Information

Product Name 3,5,6-Trichloro-2-Pyridinol Glucuronide
CAS No. 58997-12-9
Molecular Formula C11H9Cl3NO7
Molecular Weight 373.55 g/mol
Synonyms TCPy-Glucuronide; 3,5,6-Trichloro-2-pyridinyl β-D-Glucopyranosiduronic Acid; Chlorpyrifos Metabolite Glucuronide; 2-Pyridinol, 3,5,6-trichloro-, 1-(β-D-glucopyranuronosyl)-; 1-(3,5,6-Trichloro-2-pyridinyl)-β-D-glucopyranuronic acid; Glucuronide conjugate of 3,5,6-Trichloro-2-pyridinol
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Quality Control

Every batch of 3,5,6-Trichloro-2-Pyridinol Glucuronide is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for reference standard applications. A detailed Certificate of Analysis (COA) containing results for assay, related substances, and identification tests (HPLC, MS, NMR) is supplied with each shipment to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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