Description

(S)-4,5-Dihydro-3-[(1Z,7Z)-Hexadecan-7-Enylidene]-4-Hydroxy-5-Methylenefuran-2(3H)-One is a high-purity, chiral lactone derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and sophisticated building block for creating complex molecular architectures with specific stereochemistry. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly for complex natural product analogs and bioactive molecules.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the specific stereochemistry can influence biological activity and environmental fate.
• Asymmetric Synthesis: Serves as a valuable substrate or auxiliary in catalytic asymmetric reactions to construct stereogenic centers with high enantiomeric purity.
• Fragrance & Flavor Chemistry: Potential use as an intermediate for synthesizing complex macrocyclic or musk-like fragrance compounds due to its lactone structure and long alkenyl chain.
• Material Science Research: Investigated as a monomer or functional additive for specialized polymers, leveraging its reactive furanone and alkene functionalities.
• Academic & Contract Research: A critical reagent for methodological studies in organic chemistry, total synthesis projects, and process development.

Basic Information

Item	Details
Product Name	(S)-4,5-Dihydro-3-[(1Z,7Z)-Hexadecan-7-Enylidene]-4-Hydroxy-5-Methylenefuran-2(3H)-One
CAS No.	58940-65-1
Molecular Formula	C21H34O3
Molecular Weight	334.50 g/mol
Synonyms	(S)-(-)-Aspicillin; (S)-Aspicillin; (S)-4,5-Dihydro-3-[(1Z,7Z)-7-Hexadecadienylidene]-4-hydroxy-5-methyl-2(3H)-furanone; (S)-4,5-Dihydro-3-[(1Z,7Z)-hexadeca-7,9-dienylidene]-4-hydroxy-5-methylfuran-2(3H)-one; Aspicillin (S-enantiomer); (3S)-3-[(1Z,7Z)-Hexadeca-1,7-dien-1-yl]-4-hydroxy-5-methyl-5H-furan-2-one
EINECS	Contact for details

Quality Control

Our (S)-4,5-Dihydro-3-[(1Z,7Z)-Hexadecan-7-Enylidene]-4-Hydroxy-5-Methylenefuran-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess, ensuring compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.