Description

Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-2,3-Dimethyl-, (3S-Trans)- (9Ci) is a heterocyclic organic compound belonging to the pyrrolopyrazinedione class, characterized by its specific stereochemistry. This compound is valued as a versatile chiral building block and intermediate in advanced organic synthesis, particularly for the development of complex molecules with potential biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-infective agents.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for constructing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-up: Employed in the optimization and pilot-scale synthesis of target molecules, leveraging its defined stereochemistry for enantioselective routes.
• Academic Research: Utilized in universities and research institutes for studying novel organic reactions, asymmetric synthesis methodologies, and the properties of fused heterocyclic systems.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the production of other high-value fine chemicals and advanced materials requiring specific stereochemical control.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-2,3-Dimethyl-, (3S-Trans)- (9Ci)
CAS No.	58917-57-0
Molecular Formula	C8H12N2O2
Molecular Weight	168.19 g/mol
Synonyms	(3S-trans)-Hexahydro-2,3-dimethylpyrrolo[1,2-a]pyrazine-1,4-dione; (3S,3aS,8aR)-2,3-Dimethyl-3,3a,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine-1,4-dione; (3S-trans)-Hexahydro-2,3-dimethyl-1H-pyrrolo[1,2-a]pyrazine-1,4-dione; Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-2,3-dimethyl-, (3S-trans)-; 58917-57-0; (3S,3aS,8aR)-2,3-dimethyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione
EINECS	Contact for details

Quality Control

Our Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-2,3-Dimethyl-, (3S-Trans)- (9Ci) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure high chemical and stereochemical purity suitable for research and development applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture uptake. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.