Description

Ethanone, 2,2,2-Trifluoro-1-(4-Nitrophenyl)- (9Ci) is a specialized trifluoromethyl ketone derivative that serves as a high-value synthetic intermediate. This compound is critical for introducing both the trifluoromethyl and nitroaryl functional groups into target molecules, enabling the development of advanced materials and active pharmaceutical ingredients. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced material science industries for its unique electronic and steric properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and non-linear optical (NLO) chromophores.
• Fluorine Chemistry Studies: A valuable reference compound for investigating the effects of fluorine substitution on reactivity and molecular properties in academic and industrial R&D.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(4-Nitrophenyl)- (9Ci)
CAS No.	58808-61-0
Molecular Formula	C8H4F3NO3
Molecular Weight	219.12 g/mol
Synonyms	2,2,2-Trifluoro-1-(4-nitrophenyl)ethanone; 4-Nitro-α,α,α-trifluoroacetophenone; p-Nitro-α,α,α-trifluoroacetophenone; 1-(4-Nitrophenyl)-2,2,2-trifluoroethanone; 4-Nitrophenyl trifluoromethyl ketone; TFAP-NO2; α,α,α-Trifluoro-4-nitroacetophenone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(4-Nitrophenyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.