Description

(4S)-4,4Aβ,5,6,7,9-Hexahydro-4β-Hydroxy-6,6,8-Trimethylazuleno[5,6-C]Furan-1(3H)-One is a high-purity, complex sesquiterpene lactone derivative with a defined stereochemistry, valued for its role as a critical synthetic intermediate and reference standard. This compound matters for its structural complexity and potential biological activity, making it essential for advanced research and development. It is primarily needed by pharmaceutical R&D laboratories, fine chemical synthesis specialists, and analytical service providers focused on natural product chemistry and novel drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel therapeutic agents, particularly in medicinal chemistry programs targeting complex natural product derivatives.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality control of related compounds.
• Natural Product Research: Acts as a model compound or synthetic target in studies related to sesquiterpene lactones, azulene derivatives, and their associated bioactivities.
• Chemical Biology Probe: Utilized in biochemical and pharmacological assays to investigate structure-activity relationships (SAR) and biological pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for the construction of complex molecular architectures requiring specific stereocenters.
• Academic & Institutional Research: Supports fundamental research in organic chemistry, stereochemistry, and total synthesis at universities and research institutes.

Basic Information

Product Name	(4S)-4,4Aβ,5,6,7,9-Hexahydro-4β-Hydroxy-6,6,8-Trimethylazuleno[5,6-C]Furan-1(3H)-One
CAS No.	58757-92-9
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	4β-Hydroxy-6,6,8-trimethylazuleno[5,6-c]furan-1(3H)-one, (4S)-4,4a,5,6,7,9-hexahydro-; (4S)-4,4aβ,5,6,7,9-Hexahydro-4β-hydroxy-6,6,8-trimethylazuleno[5,6-c]furan-1(3H)-one; Azuleno[5,6-c]furan-1(3H)-one derivative; Sesquiterpene lactone derivative; (4S,4aR,6S,8R)-4,4a,5,6,7,9-Hexahydro-4-hydroxy-6,6,8-trimethylazuleno[5,6-c]furan-1(3H)-one (stereospecific); Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our (4S)-4,4Aβ,5,6,7,9-Hexahydro-4β-Hydroxy-6,6,8-Trimethylazuleno[5,6-C]Furan-1(3H)-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.