Description

2-Bromo-1-[4-(Piperidin-1-Ylsulfonyl)Phenyl]Ethanone is a specialized organic building block featuring a bromoacetyl group linked to a piperidine sulfonyl-substituted aromatic ring. This molecular architecture makes it a valuable intermediate for the synthesis of more complex pharmacologically active compounds, particularly in medicinal chemistry research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel chemical entities. The compound's reactivity profile allows for selective functionalization, enabling the development of targeted libraries for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting enzymes or receptors where the sulfonyl and bromoacetyl groups are crucial for activity.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization stages to explore structure-activity relationships (SAR) and create analogs for biological screening.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, or insecticides, leveraging its reactive sites for further chemical modification.
• Chemical Biology Probes: Serves as a starting material for creating activity-based probes (ABPs) or affinity labels to study protein function and interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and the development of new catalytic or coupling reactions.

Basic Information

Item	Detail
Product Name	2-Bromo-1-[4-(Piperidin-1-Ylsulfonyl)Phenyl]Ethanone
CAS No.	58722-39-7
Molecular Formula	C13H16BrNO3S
Molecular Weight	346.24 g/mol
Synonyms	2-Bromo-1-[4-(1-Piperidinosulfonyl)phenyl]ethanone; 1-[4-(Piperidin-1-Ylsulfonyl)Phenyl]-2-Bromoethanone; 2-Bromo-1-(4-piperidine-1-sulfonylphenyl)ethanone; 4'-(Piperidin-1-Ylsulfonyl)phenacyl Bromide; α-Bromo-4-(piperidin-1-ylsulfonyl)acetophenone; 58722-39-7; Ethanone, 2-bromo-1-[4-(1-piperidinylsulfonyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-[4-(Piperidin-1-Ylsulfonyl)Phenyl]Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality commitment supports applications requiring high-purity chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its light-sensitive nature, the container should be opaque or stored in dark conditions. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.