Description

o-Tolyl-Propynoic Acid Ethyl Ester is a specialized organic ester building block featuring a propynoate group linked to an o-tolyl (ortho-methylphenyl) moiety. This compound matters as a versatile intermediate for synthesizing more complex molecules, particularly in fine chemical and pharmaceutical research where its alkyne and ester functionalities enable targeted chemical modifications. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those requiring an ortho-substituted aromatic scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional polymers.
• Chemical Biology Probes: Utilized as a synthetic handle for creating molecular probes to study biological processes via click chemistry or other bioorthogonal reactions.
• Fine Chemical Production: Intermediate for the manufacture of dyes, flavors, fragrances, and other specialty chemicals.

Basic Information

Item	Detail
Product Name	o-Tolyl-Propynoic Acid Ethyl Ester
CAS No.	58686-71-8
Molecular Formula	C₁₂H₁₂O₂
Molecular Weight	188.22 g/mol
Synonyms	Ethyl 2-Methylphenylpropiolate; Ethyl o-Tolylpropiolate; Ethyl (2-Methylphenyl)propynoate; 2-Methylphenylpropiolic Acid Ethyl Ester; o-Tolylpropiolic Acid Ethyl Ester; Propiolic Acid, o-Tolyl-, Ethyl Ester; Ethyl 2-Methylbenzene-1-propiolate
EINECS	Contact for details

Quality Control

Our o-Tolyl-Propynoic Acid Ethyl Ester is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.