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2-O,3-O:4-O,5-o-Bis(Butylboranediyl)-β-D-Fructopyranose 1-(Phosphoric Acid Dimethyl) Ester CAS NO 58634-46-1


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CAS No.:58634-46-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-O,3-O:4-O,5-o-Bis(Butylboranediyl)-β-D-Fructopyranose 1-(Phosphoric Acid Dimethyl) Ester is a sophisticated organoboron-sugar phosphate derivative, representing a key intermediate in advanced synthetic chemistry. This compound is valued for its unique structure, which combines a protected fructose core with boronate ester and phosphate ester functionalities, enabling precise control in complex molecular assembly. It is primarily utilized by research institutions and pharmaceutical development teams working on nucleoside analogs, prodrug strategies, and targeted boron-based therapeutics.

Application

  • Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside or nucleotide analogs for antiviral and anticancer research.
  • Prodrug Development: Used to create phosphate-protected prodrugs designed for improved cellular uptake and targeted release of active pharmaceutical ingredients (APIs).
  • Boron Neutron Capture Therapy (BNCT) Agents: Serves as a precursor in the development of boron-containing compounds for targeted cancer therapies.
  • Glycoconjugate Chemistry: Employed in the synthesis of complex glycoconjugates and labeled sugars for biochemical studies and diagnostic applications.
  • Chemical Biology Tool: Acts as a specialized reagent for studying enzyme mechanisms, particularly those involving sugar phosphates and kinases.
  • Advanced Material Synthesis: Potential use as a monomer or cross-linker in the development of smart polymeric materials with responsive properties.

Basic Information

Item Detail
Product Name 2-O,3-O:4-O,5-o-Bis(Butylboranediyl)-β-D-Fructopyranose 1-(Phosphoric Acid Dimethyl) Ester
CAS No. 58634-46-1
Molecular Formula C16H31B2O9P
Molecular Weight 428.00 g/mol (Contact for details)
Synonyms Dimethyl (2-O,3-O:4-O,5-o-Bis(butylboranediyl)-β-D-fructopyranos-1-yl) Phosphate; 1-(Dimethylphosphoryl)-2,3:4,5-bis-O-(butylboranediyl)-β-D-fructopyranose; Fructopyranose Bis(butylboronate) Dimethyl Phosphate Ester; CAS 58634-46-1; Butylboronate-Protected Fructose Phosphate
EINECS Contact for details

Quality Control

Every batch of 2-O,3-O:4-O,5-o-Bis(Butylboranediyl)-β-D-Fructopyranose 1-(Phosphoric Acid Dimethyl) Ester is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity, purity, and impurity profile testing using advanced analytical techniques (NMR, HPLC, MS) to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) when opening to prevent degradation. For long-term stability, consider storage under desiccant.

Specification

Item Specification
Appearance White to off-white solid
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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