Description

Saikosaponin B4 is a bioactive triterpenoid saponin primarily isolated from the roots of *Bupleurum* species, a key herb in traditional medicine. This high-purity compound is valued for its significant role in pharmaceutical research and development, particularly for its anti-inflammatory and hepatoprotective properties. It serves as a critical reference standard and active ingredient for manufacturers in the pharmaceutical, nutraceutical, and advanced research sectors.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of Bupleurum-based products in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key starting material or intermediate in the synthesis of novel therapeutic agents.
• Nutraceutical Formulations: Incorporated into high-end dietary supplements targeting liver health and immune system modulation.
• Biomedical Research: Employed in *in vitro* and *in vivo* studies to investigate mechanisms of inflammation, viral infection, and metabolic disorders.
• Cosmeceutical Development: Explored for its potential anti-inflammatory benefits in topical skincare formulations.
• Traditional Medicine Standardization: Essential for standardizing extracts of Bupleurum (Chai Hu) to ensure consistent potency and efficacy.

Basic Information

Product Name	Saikosaponin B4
CAS No.	58558-09-1
Molecular Formula	C42H68O13
Molecular Weight	780.98 g/mol
Synonyms	Saikosaponin B4; (3β,4α,16β)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→3)-β-D-fucopyranoside; Chikusetsusaponin IVa; SS-B4; Bupleurum saponin B4
EINECS	Contact for details

Quality Control

Our Saikosaponin B4 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Solvent Residues	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.