Description

6-Fluoro-1,2,3,4-Tetrahydronaphthalen-1-Ol is a fluorinated tetralin derivative, a versatile chiral building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a fluorine atom and a hydroxyl group on a partially saturated naphthalene scaffold, enabling precise modulation of molecular properties. This compound is primarily needed by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients, where its structure serves as a key intermediate.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of central nervous system (CNS) active drugs, receptor modulators, and other bioactive molecules.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Asymmetric Catalysis & Ligand Development: Employed in the synthesis of complex chiral ligands and catalysts for enantioselective transformations.
• Flavor & Fragrance Chemistry: Acts as an intermediate for synthesizing novel aromatic compounds with unique olfactory properties.
• Academic & Contract Research: A valuable reagent for methodological studies in fluorination chemistry and stereoselective synthesis at universities and CROs.

Basic Information

Product Name	6-Fluoro-1,2,3,4-Tetrahydronaphthalen-1-Ol
CAS No.	58485-69-1
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	6-Fluoro-1-tetralol; 6-Fluoro-1,2,3,4-tetrahydro-1-naphthol; 1-Hydroxy-6-fluoro-1,2,3,4-tetrahydronaphthalene; (1RS)-6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-ol; 6-Fluoro-α-tetralol; 6-Fluoro-1-hydroxy-1,2,3,4-tetrahydronaphthalene; 6-Fluoro-1,2,3,4-tetrahydro-1-naphthalenol
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1,2,3,4-Tetrahydronaphthalen-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.