Description

2-(4-Bromophenyl)-2-Hydroxyacetonitrile (Wx191375) is a versatile and high-purity organic building block, specifically a cyanohydrin derivative, essential for advanced synthetic chemistry. Its core value lies in providing a reactive nitrile and hydroxyl group on a brominated aromatic scaffold, enabling precise molecular construction. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing complex active ingredients and novel intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing chiral centers or aryl bromine handles for further functionalization via cross-coupling reactions.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the reactivity of the cyanohydrin and the bromophenyl moiety.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis or as a starting material for metal-organic frameworks (MOFs) and other advanced materials.
• Fine Chemical Production: Employed in the multi-step synthesis of dyes, pigments, and other performance chemicals requiring specific aromatic architectures.
• Academic and R&D Laboratories: A valuable reagent for methodological research in organic synthesis, including studies on cyanohydrin chemistry and palladium-catalyzed transformations.

Basic Information

Product Name	2-(4-Bromophenyl)-2-Hydroxyacetonitrile (Wx191375)
CAS No.	58289-69-3
Molecular Formula	C8H6BrNO
Molecular Weight	212.04 g/mol
Synonyms	4-Bromomandelonitrile; (4-Bromophenyl)(hydroxy)acetonitrile; α-Hydroxy-4-bromobenzeneacetonitrile; 2-Hydroxy-2-(4-bromophenyl)acetonitrile; 4-Bromo-α-hydroxybenzeneacetonitrile; p-Bromomandelonitrile; WX-191375
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-2-Hydroxyacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.