Description

Tris(2,2,2-trifluoroethyl) orthoformate is a specialized fluorinated orthoester derivative, serving as a versatile reagent and building block in advanced organic synthesis. Its primary value lies in its ability to act as a protected formyl synthon and a source of trifluoroethoxide under specific conditions, enabling the introduction of fluorine-containing moieties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the production of advanced, fluorinated pesticides and herbicides to enhance their biological activity and environmental stability.
• Fluorinated Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and electronic materials with unique surface properties.
• Organic Synthesis Reagent: Functions as a protecting group for aldehydes or as a trifluoroethylating agent in complex multi-step synthetic routes.
• Fine Chemical Production: Employed in the manufacture of high-value fluorinated fragrances, dyes, and liquid crystals.

Basic Information

Product Name	Tris(2,2,2-trifluoroethyl) orthoformate
CAS No.	58244-27-2
Molecular Formula	C7H7F9O3
Molecular Weight	310.12 g/mol
Synonyms	1,1',1''-Methanetriyltris(2,2,2-trifluoroethanol); Orthoformic Acid Tris(2,2,2-trifluoroethyl) Ester; Tris(2,2,2-trifluoroethoxy)methane; Tris(β,β,β-trifluoroethyl) Orthoformate; HC(OCH2CF3)3; Trifluoroethyl Orthoformate; TTFEO
EINECS	Contact for details

Quality Control

Our Tris(2,2,2-trifluoroethyl) orthoformate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.