Description

1-tert-Butyl-3-Iodobenzene is a high-purity, substituted aromatic compound featuring a tert-butyl group and an iodine atom in meta positions on the benzene ring. This specific substitution pattern makes it a valuable and versatile building block in advanced organic synthesis, particularly for cross-coupling reactions. It is primarily used by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to create complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura, Stille, or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used to construct novel herbicide and pesticide molecules, leveraging the iodine as a reactive handle for introducing complex side chains.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs or conductive polymers.
• Ligand and Catalyst Development: Employed to synthesize sophisticated phosphine or N-heterocyclic carbene (NHC) ligands for asymmetric catalysis.
• Chemical Biology Probes: Useful for creating tagged molecules or bioconjugates for imaging and diagnostic applications due to the reactivity of the iodine atom.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	1-tert-Butyl-3-Iodobenzene
CAS No.	58164-02-6
Molecular Formula	C10H13I
Molecular Weight	260.12 g/mol
Synonyms	3-tert-Butyliodobenzene; 1-Iodo-3-tert-butylbenzene; m-tert-Butyliodobenzene; 3-(tert-Butyl)iodobenzene; (3-tert-Butylphenyl)iodide; 3-Iodo-1-tert-butylbenzene; Benzene, 1-tert-butyl-3-iodo-; 3-tert-Butylphenyl iodide
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-3-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.