Description

1-(4-Chloro-Phenyl)-2-Pyridin-4-Yl-Ethanone is a high-purity organic building block featuring both a chlorophenyl and a pyridinyl moiety. This compound is valued for its role as a versatile synthetic intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a critical building block for developing novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic system.
• Ligand and Catalyst Development: Used in research to create novel pyridine-based ligands for metal-catalyzed coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials due to its conjugated structure.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	1-(4-Chloro-Phenyl)-2-Pyridin-4-Yl-Ethanone
CAS No.	58158-45-5
Molecular Formula	C13H10ClNO
Molecular Weight	231.68 g/mol
Synonyms	4'-Chloro-4-pyridyl acetophenone; 1-(4-Chlorophenyl)-2-(4-pyridinyl)ethanone; 4-Pyridyl 4-chlorophenyl ketone; p-Chlorophenyl 4-pyridyl ketone; 4-Acetylpyridine, 4'-chloro derivative; 4-(4-Chlorobenzoyl)pyridine; (4-Chlorophenyl)(4-pyridinyl)methanone
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-Phenyl)-2-Pyridin-4-Yl-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.