Description

2-Buten-1-One, 2-Fluoro-1-Phenyl- (9Ci) is a specialized fluorinated α,β-unsaturated ketone building block. This compound is valued for its unique reactivity profile, where the fluorine atom and the conjugated enone system enable precise synthetic modifications. It is primarily sought by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex molecular architectures, including potential active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, leveraging the fluorine atom for metabolic stability and bioavailability.
• Agrochemical Research: Used in developing novel fluorinated pesticides and herbicides, where the fluorine moiety can enhance biological activity and environmental persistence.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers with tailored optical or surface properties.
• Organic Synthesis: Employed in Michael addition reactions, cycloadditions, and other C-C bond-forming transformations to introduce fluorinated phenyl ketone motifs.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for studying biological mechanisms and interactions.

Basic Information

Product Name	2-Buten-1-One, 2-Fluoro-1-Phenyl- (9Ci)
CAS No.	58089-74-0
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	2-Fluoro-1-phenyl-2-buten-1-one; 2-Fluoro-1-phenylbut-2-en-1-one; (E/Z)-2-Fluoro-1-phenyl-2-buten-1-one; α-Fluoro-β-methylcinnamaldehyde (keto form); Fluorinated phenyl vinyl ketone; 2-Fluoro chalcone derivative; 58089-74-0; 2-Fluoro-1-phenylbut-2-enone
EINECS	Contact for details

Quality Control

Every batch of 2-Buten-1-One, 2-Fluoro-1-Phenyl- (9Ci) is subjected to rigorous analytical testing to ensure identity, purity, and consistency. Our quality protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or GC), identity confirmation (by IR and NMR), and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and potential reactivity with strong bases and fluorides, the container should be kept tightly sealed and separated from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Isomer Ratio (E/Z)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.