Description

1-Propanone, 2-Fluoro-3-Hydroxy-2-(Hydroxymethyl)-1-(4-Methylphenyl)- (9Ci) is a specialized fluorinated aromatic ketone derivative, serving as a high-value synthetic intermediate. Its unique structure, featuring both fluorine and multiple hydroxyl groups, makes it a critical building block for constructing complex molecules with tailored properties. This compound is essential for research and development in advanced pharmaceutical synthesis and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for metabolic stability.
• Agrochemical Research: Used in developing advanced crop protection agents, where the fluorine atom can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Complex Ligand & Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Advanced Polymer Modification: Used to introduce functional hydroxyl and fluorinated side chains into polymer backbones, altering physical and chemical properties for specialty coatings and adhesives.

Basic Information

Product Name	1-Propanone, 2-Fluoro-3-Hydroxy-2-(Hydroxymethyl)-1-(4-Methylphenyl)- (9Ci)
CAS No.	58089-67-1
Molecular Formula	C11H13FO3
Molecular Weight	212.22 g/mol
Synonyms	2-Fluoro-3-hydroxy-2-(hydroxymethyl)-1-(4-methylphenyl)propan-1-one; 1-(4-Methylphenyl)-2-fluoro-3-hydroxy-2-(hydroxymethyl)-1-propanone; 2-Fluoro-2-(hydroxymethyl)-3-hydroxy-1-p-tolylpropan-1-one; α-Fluoro-β,β-dihydroxy-p-methylpropiophenone; 58089-67-1; Fluorinated p-methylpropiophenone derivative
EINECS	Contact for details

Quality Control

Our 1-Propanone, 2-Fluoro-3-Hydroxy-2-(Hydroxymethyl)-1-(4-Methylphenyl)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC-MS, and NMR for identity confirmation and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.