Description

Rac-(1R,2R,4R)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid is a versatile chiral bicyclic building block of significant interest in advanced organic synthesis. Its rigid norbornene framework and carboxylic acid functionality make it a valuable precursor for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially those requiring rigid, three-dimensional scaffolds.
• Chiral Ligand & Catalyst Development: Serves as a precursor for creating sophisticated ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Polymer Science: Used as a monomer or co-monomer in the production of specialty polymers with unique thermal and mechanical properties via ring-opening metathesis polymerization (ROMP).
• Material Science Research: Employed in the development of advanced materials, including liquid crystals and functionalized surfaces.
• Agrochemical Synthesis: Acts as a building block for creating novel, biologically active compounds with potential pesticidal or herbicidal activity.
• Academic & R&D: A fundamental reagent in organic chemistry research for studying reaction mechanisms and exploring new synthetic methodologies.

Basic Information

Product Name	Rac-(1R,2R,4R)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid
CAS No.	58001-99-3
Molecular Formula	C8H10O2
Molecular Weight	138.16 g/mol
Synonyms	(±)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; rac-endo-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; 5-Norbornene-2-carboxylic acid; endo-5-Norbornene-2-carboxylic acid; (±)-endo-5-Norbornene-2-carboxylic acid; NSC 106977; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, (±)-
EINECS	Contact for details

Quality Control

Our Rac-(1R,2R,4R)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Raccemic mixture
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.