Description

6-[(Trifluoroacetyl)Amino]Hexanoic Acid 1-Methylpropyl Ester is a specialized fluorinated organic building block that provides a unique combination of a reactive ester group and a trifluoroacetyl-protected amine. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research where the introduction of fluorine atoms is critical for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing peptide mimetics, prodrugs, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated amino acid derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides where fluorine substitution enhances efficacy and environmental persistence.
• Peptide & Prodrug Chemistry: Serves as a protected building block for constructing modified peptide chains or as a linker in prodrug design to improve bioavailability.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty coatings to impart unique surface properties and chemical resistance.
• Chemical Biology Probes: Utilized as a reagent for labeling and modifying biomolecules in diagnostic and research applications.
• Organic Synthesis Reagent: Acts as a versatile acylating agent or protected amine precursor in multi-step synthetic routes for complex organic molecules.

Basic Information

Product Name	6-[(Trifluoroacetyl)Amino]Hexanoic Acid 1-Methylpropyl Ester
CAS No.	57983-24-1
Molecular Formula	C12H20F3NO3
Molecular Weight	283.29 g/mol
Synonyms	1-Methylpropyl 6-[(2,2,2-Trifluoroacetyl)amino]hexanoate; sec-Butyl 6-[(Trifluoroacetyl)amino]hexanoate; 6-(Trifluoroacetamido)hexanoic Acid sec-Butyl Ester; N-(5-Carboxybutyl)-2,2,2-trifluoroacetamide sec-Butyl Ester; 6-(Trifluoroacetylamino)caproic Acid 1-Methylpropyl Ester; 6-TFA-Aminohexanoic Acid sec-Butyl Ester; Hexanoic acid, 6-[(trifluoroacetyl)amino]-, 1-methylpropyl ester
EINECS	Contact for details

Quality Control

Our 6-[(Trifluoroacetyl)Amino]Hexanoic Acid 1-Methylpropyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.