Description

n-(Trifluoroacetyl)-L-Alanine 1-Methylbutyl Ester CAS NO 57983-11-6 is a specialized chiral building block and derivatization reagent used in advanced organic synthesis. This compound is valued for its role in introducing the trifluoroacetyl protecting group and the L-alanine moiety, which is critical for modulating the properties of target molecules. It is primarily required by research and development laboratories, as well as production facilities, in the pharmaceutical and agrochemical sectors for the synthesis of peptides, chiral intermediates, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in peptide-based drug discovery.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to construct specific peptide sequences.
• Agrochemical Research: Serves as a building block for creating chiral compounds with potential herbicidal or insecticidal activity.
• Derivatization Agent: Employed in analytical chemistry to derivative amino acids or other compounds for enhanced detection via chromatography or mass spectrometry.
• Chemical Biology Probes: Utilized in the synthesis of labeled or modified biomolecules for studying biological mechanisms and interactions.
• Asymmetric Synthesis: Acts as a source of chirality in catalytic asymmetric reactions to produce enantiomerically enriched compounds.

Basic Information

Product Name	n-(Trifluoroacetyl)-L-Alanine 1-Methylbutyl Ester
CAS No.	57983-11-6
Molecular Formula	C10H16F3NO3
Molecular Weight	255.24 g/mol
Synonyms	L-Alanine, N-(trifluoroacetyl)-, 1-methylbutyl ester; 1-Methylbutyl N-(trifluoroacetyl)-L-alaninate; N-(Trifluoroacetyl)alanine 1-methylbutyl ester; N-[(2,2,2-Trifluoroacetyl)-L-alanine] 1-methylbutyl ester; (S)-1-Methylbutyl 2-(2,2,2-trifluoroacetamido)propanoate; 57983-11-6; Alanine derivative, TFA-L-Ala-OMeBu
EINECS	Contact for details

Quality Control

Our n-(Trifluoroacetyl)-L-Alanine 1-Methylbutyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.