Description

2-Methyl-2-(Trifluoroacetylamino)Propionic Acid 1-Methylpropyl Ester is a specialized fluorinated organic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both a trifluoroacetyl-protected amino group and an ester moiety, makes it a valuable intermediate for introducing specific functionalities into target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and fine chemicals with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can improve metabolic stability and bioavailability.
• Peptide Mimetics & Prodrug Development: The protected amino acid ester structure is valuable for creating peptide analogs and designing prodrug strategies to enhance drug delivery.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials with specific surface properties.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic research applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences industry, enabling the production of complex, tailor-made molecules.

Basic Information

Product Name	2-Methyl-2-(Trifluoroacetylamino)Propionic Acid 1-Methylpropyl Ester
CAS No.	57983-07-0
Molecular Formula	C10H16F3NO3
Molecular Weight	255.24 g/mol
Synonyms	2-Methyl-2-[(2,2,2-trifluoroacetyl)amino]propanoic acid 1-methylpropyl ester; sec-Butyl 2-methyl-2-(trifluoroacetylamino)propionate; 2-(Trifluoroacetamido)isobutyric acid sec-butyl ester; N-(Trifluoroacetyl)-2-aminoisobutyric acid sec-butyl ester; 2-Methyl-2-(trifluoroacetamido)propionic acid sec-butyl ester; TFAA-Ibu-O-sec-Bu; sec-Butyl 2-(2,2,2-trifluoroacetamido)-2-methylpropanoate
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-(Trifluoroacetylamino)Propionic Acid 1-Methylpropyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is sensitive to fluoride/strong alkali conditions. Keep away from incompatible materials such as strong bases. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.