Description

p-(2-Benzoxazolyl)Benzyl Chloride is a specialized organic intermediate featuring a benzoxazole moiety linked to a reactive benzyl chloride group. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in advanced material and pharmaceutical research. It is primarily sought by R&D chemists and process development teams in the fine chemical, agrochemical, and pharmaceutical industries for constructing novel heterocyclic frameworks and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, where the benzoxazole unit can contribute to biological activity.
• Liquid Crystal & OLED Material Research: Acts as a building block for creating advanced organic electronic materials, such as charge-transport layers or emissive dopants in display technologies.
• Fluorescent Probe & Dye Development: The benzoxazole core is a classic fluorophore, making this intermediate valuable for synthesizing sensors and imaging agents.
• Polymer Modification: Employed to introduce photoactive or stabilizing benzoxazole groups into polymer chains to enhance material properties like UV resistance.
• Cross-coupling Reactions: The benzyl chloride group facilitates further functionalization via palladium-catalyzed or other metal-mediated coupling reactions.

Basic Information

Product Name	p-(2-Benzoxazolyl)Benzyl Chloride
CAS No.	57864-19-4
Molecular Formula	C14H10ClNO
Molecular Weight	243.69 g/mol
Synonyms	4-(Benzoxazol-2-yl)benzyl Chloride; 1-(Chloromethyl)-4-(1,3-benzoxazol-2-yl)benzene; 2-(4-(Chloromethyl)phenyl)benzoxazole; p-(2-Benzoxazolyl)benzyl Chloride; 4-(2-Benzoxazolyl)benzyl Chloride; NSC 403119; Benzyl chloride, p-(2-benzoxazolyl)-
EINECS	Contact for details

Quality Control

Our p-(2-Benzoxazolyl)Benzyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.