Description

2-Bromomethyl-Terephthalic Acid Dimethyl Ester is a high-purity, versatile brominated aromatic ester that serves as a critical building block in advanced organic synthesis. Its primary value lies in its reactive bromomethyl group, which enables efficient functionalization and chain extension for creating complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop new active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its aromatic core for bioactivity.
• Liquid Crystal & OLED Material Production: Serves as a foundational monomer for constructing rigid, conjugated structures essential in electronic display and lighting technologies.
• Polymer Modification: Employed to introduce functional groups into polymer backbones, enhancing properties like adhesion, thermal stability, or solubility for advanced coatings and engineering plastics.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for creating biaryl and complex aromatic systems in medicinal chemistry.
• Academic & Contract Research: A reliable reagent for methodological development and exploring new reaction pathways in organic and medicinal chemistry laboratories.

Basic Information

Product Name	2-Bromomethyl-Terephthalic Acid Dimethyl Ester
CAS No.	57834-13-6
Molecular Formula	C12H13BrO4
Molecular Weight	301.14 g/mol
Synonyms	Dimethyl 2-(bromomethyl)terephthalate; 2-(Bromomethyl)terephthalic Acid Dimethyl Ester; 1,4-Benzenedicarboxylic acid, 2-(bromomethyl)-, dimethyl ester; Terephthalic acid, 2-(bromomethyl)-, dimethyl ester; Dimethyl 2-bromomethylterephthalate; 2-Bromomethyl-1,4-benzenedicarboxylic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Every batch of 2-Bromomethyl-Terephthalic Acid Dimethyl Ester is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards through rigorous analytical protocols, including HPLC, GC, and NMR spectroscopy, to guarantee identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.