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Triphenyl[(2E,6E,10E)-3,7,11,15-Tetramethyl-2,6,10,14-Hexadecatetraenyl]Phosphonium Bromide CAS NO 57784-37-9


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CAS No.:57784-37-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Triphenyl[(2E,6E,10E)-3,7,11,15-Tetramethyl-2,6,10,14-Hexadecatetraenyl]Phosphonium Bromide is a high-purity, synthetic phosphonium salt derivative of farnesol, serving as a critical Wittig reagent in advanced organic synthesis. Its primary value lies in enabling the stereoselective construction of polyene chains, a key structural motif in biologically active compounds. This specialized reagent is essential for researchers and manufacturers in pharmaceutical development, particularly for synthesizing retinoids, carotenoids, and other complex isoprenoid-based molecules.

Application

  • Pharmaceutical Intermediate Synthesis: Key reagent for the stereocontrolled synthesis of vitamin A analogs, retinoids, and other therapeutic agents targeting nuclear receptors.
  • Fine Chemical Production: Used in the construction of complex polyene backbones for specialty chemicals, flavors, and fragrances.
  • Academic & Industrial Research: A vital tool in medicinal chemistry and total synthesis projects for building specific carbon-carbon double bonds via the Wittig olefination reaction.
  • Nutraceutical Precursor Development: Employed in the research and development of carotenoid and other isoprenoid-based nutritional supplements.
  • Material Science Research: Potential use in synthesizing organic semiconductors or light-harvesting materials with extended conjugated systems.

Basic Information

Product Name Triphenyl[(2E,6E,10E)-3,7,11,15-Tetramethyl-2,6,10,14-Hexadecatetraenyl]Phosphonium Bromide
CAS No. 57784-37-9
Molecular Formula C₃₈H₄₇BrP
Molecular Weight 605.66 g/mol
Synonyms Farnesyltriphenylphosphonium Bromide; (2E,6E)-Farnesyltriphenylphosphonium Bromide; (all-E)-3,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraen-1-yl-triphenylphosphonium Bromide; Triphenyl(farnesyl)phosphonium Bromide; (E,E,E)-Farnesyltriphenylphosphonium Bromide; P-[(2E,6E,10E)-3,7,11,15-Tetramethyl-2,6,10,14-Hexadecatetraen-1-yl]-triphenylphosphonium Bromide
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Quality Control

Our Triphenyl[(2E,6E,10E)-3,7,11,15-Tetramethyl-2,6,10,14-Hexadecatetraenyl]Phosphonium Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and reactivity.

Specification

Item Specification
Appearance White to pale yellow crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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