Description

9,12α,13-Trihydroxy-17-Norkaurane-11,16-Dione is a highly functionalized diterpenoid derivative, a key intermediate in the synthesis of complex natural products and pharmaceuticals. Its intricate kaurane skeleton and multiple oxygen functionalities make it a valuable scaffold for medicinal chemistry research and the development of novel bioactive compounds. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of terpenoid-based drug candidates and advanced chemical probes.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel diterpenoid-based drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Natural Product Synthesis: Serves as a key intermediate in the total or semi-synthesis of complex natural products with kaurane or related diterpenoid skeletons.
• Chemical Biology: Employed in the development of chemical probes to study biological pathways and enzyme functions related to terpenoid metabolism.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in laboratories analyzing terpenoid compounds.

Basic Information

Product Name	9,12α,13-Trihydroxy-17-Norkaurane-11,16-Dione
CAS No.	57743-95-0
Molecular Formula	C₁₉H₂₈O₅
Molecular Weight	336.42 g/mol
Synonyms	17-Norkaurane-11,16-dione, 9,12α,13-trihydroxy-; 9,12α,13-Trihydroxy-17-norkauran-11,16-dione; 9,12α,13-Trihydroxy-17-norkaurane-11,16-dione; 17-Nor-kaurane-11,16-dione, 9,12α,13-trihydroxy-; Ent-9,12α,13-Trihydroxy-17-norkauran-11,16-dione; (4α,5β,8α,9α,12α)-9,12,13-Trihydroxy-17-norkauran-11,16-dione
EINECS	Contact for details

Quality Control

Our 9,12α,13-Trihydroxy-17-Norkaurane-11,16-Dione is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the primary container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.