Description

Ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is a high-purity, semi-synthetic diterpenoid derivative of the kaurane class. This compound serves as a critical advanced pharmaceutical intermediate and a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel anti-inflammatory, anti-cancer, or neuroprotective drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies and lead optimization programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.
• Natural Product Derivative Synthesis: A starting material for creating analogs of bioactive natural products derived from the kaurane diterpenoid family.
• Biochemical Research: Investigated for its potential interactions with specific enzymes or biological pathways in preclinical studies.
• Agrochemical Development: Potential intermediate in the research and development of new plant growth regulators or protective agents.

Basic Information

Product Name	Ent-11α-Hydroxy-15-oxokaur-16-en-19-oic Acid
CAS No.	57719-81-0
Molecular Formula	C₂₀H₂₈O₄
Molecular Weight	332.44 g/mol
Synonyms	11α-Hydroxy-15-oxokaur-16-en-19-oic Acid; (-)-11α-Hydroxy-15-oxokaur-16-en-19-oic Acid; ent-Kaur-16-en-19-oic acid, 11α-hydroxy-15-oxo-; 15-Oxo-11α-hydroxykaur-16-en-19-oic Acid; 11α-Hydroxy-15-oxo-kaur-16-en-19-oic Acid; KA-003; A kaurane diterpenoid derivative.
EINECS	Contact for details

Quality Control

Our Ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.