Description

(1R)-1,4,4Aβ,4B,5,6,7,8,8Aβ,9,10,10Aα-Dodecahydro-4Bα,8,8-Trimethylphenanthren-1α-Ol is a high-purity, stereochemically defined decalin derivative with significant utility as a key chiral intermediate in advanced organic synthesis. Its rigid, polycyclic framework makes it a valuable building block for constructing complex molecular architectures, particularly in the pharmaceutical and fine chemical sectors. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs), fragrances, and specialty materials where precise stereochemistry is critical for function and performance.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of steroidal analogs, complex natural products, and other bioactive molecules.
• Fine Chemical Synthesis: Used as a building block in the production of high-value specialty chemicals, catalysts, and ligands.
• Fragrance & Flavor Industry: Serves as a precursor for the development of novel, structurally unique aroma chemicals with specific olfactory properties.
• Material Science Research: Employed in the development of liquid crystals, organic semiconductors, and other advanced functional materials due to its rigid backbone.
• Academic & R&D: A valuable reference standard and starting material for methodological studies in asymmetric synthesis and total synthesis projects.

Basic Information

Product Name	(1R)-1,4,4Aβ,4B,5,6,7,8,8Aβ,9,10,10Aα-Dodecahydro-4Bα,8,8-Trimethylphenanthren-1α-Ol
CAS No.	57684-14-7
Molecular Formula	C19H32O
Molecular Weight	276.46 g/mol
Synonyms	(1R)-Decahydro-4b,8,8-trimethylphenanthren-1-ol; (1R)-1,2,3,4,4a,4b,5,6,7,8,8a,9,10,10a-Tetradecahydro-4b,8,8-trimethylphenanthren-1-ol; (1R)-Perhydro-4b,8,8-trimethylphenanthren-1-ol; 1α-ol, 4b,8,8-Trimethyldecahydrophenanthrene; (1R)-4b,8,8-Trimethyldecahydrophenanthren-1α-ol; A key isomer of decalin-based terpenoid alcohols.
EINECS	Contact for details

Quality Control

Our (1R)-1,4,4Aβ,4B,5,6,7,8,8Aβ,9,10,10Aα-Dodecahydro-4Bα,8,8-Trimethylphenanthren-1α-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and structural confirmation by NMR and IR spectroscopy, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.