Description

Baccatin Vi CAS NO 57672-79-4 is a key diterpenoid intermediate and a vital precursor in the semi-synthesis of the potent anticancer drug paclitaxel (Taxol). Its consistent high purity is critical for ensuring the efficacy and safety of the final pharmaceutical product. This compound is essential for research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in oncology drug development and production.

Application

• Pharmaceutical Intermediate: Primary use as a crucial precursor in the semi-synthetic production of paclitaxel and related taxane derivatives.
• Oncology Drug Research: Serves as a key starting material in medicinal chemistry for developing novel anticancer agents and analogs.
• Biochemical Research: Used in studies investigating tubulin polymerization, cell cycle arrest, and apoptosis mechanisms.
• Reference Standard: Employed as a high-purity analytical standard for quality control (QC) and quality assurance (QA) in pharmaceutical manufacturing.
• Process Development: Utilized in scaling up and optimizing synthetic pathways for taxane-based pharmaceuticals.

Basic Information

Product Name	Baccatin Vi
CAS No.	57672-79-4
Molecular Formula	C31H38O11
Molecular Weight	586.63 g/mol
Synonyms	Baccatin VI; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one; 10-Deacetylbaccatin V; NSC 330836; 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-
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Quality Control

Our Baccatin Vi is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.