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2-Ethyl-4,5-Dimethyl-1,3,2-Dioxaborolane CAS NO 57633-64-4


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CAS No.:57633-64-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Ethyl-4,5-Dimethyl-1,3,2-Dioxaborolane is a specialized organoboron compound belonging to the class of cyclic boronic esters. This chemical is valued for its role as a versatile building block and protecting group in advanced organic synthesis, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research chemists and process development scientists for applications in cross-coupling reactions, Suzuki-Miyaura couplings, and the synthesis of complex bioactive molecules.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
  • Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and plant growth regulators.
  • Material Science: Serves as a monomer or cross-linking agent in the production of advanced polymers and boron-containing materials.
  • Organic Synthesis Reagent: Acts as a stable boronate ester reagent in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura couplings.
  • Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and reaction pathways.
  • Ligand and Catalyst Development: Utilized in the preparation of novel ligands and catalysts for asymmetric synthesis.

Basic Information

Item Details
Product Name 2-Ethyl-4,5-Dimethyl-1,3,2-Dioxaborolane
CAS No. 57633-64-4
Molecular Formula C7H13BO2
Molecular Weight 140.00 g/mol
Synonyms 2-Ethyl-4,5-dimethyl-1,3,2-dioxaborolane; 4,5-Dimethyl-2-ethyl-1,3,2-dioxaborolane; Ethyl Dimethyl Dioxaborolane; Cyclic Ethylboronate; 1,3,2-Dioxaborolane, 2-ethyl-4,5-dimethyl-; Boronic acid, ethyl-, cyclic ester with 2,3-butanediol
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Quality Control

Our 2-Ethyl-4,5-Dimethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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