Description

4-Fluoro-2,3-Dihydro-1H-Indene is a fluorinated indane derivative, a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring a fluorine atom on the aromatic ring fused to a saturated five-membered ring, makes it a critical intermediate for developing novel compounds with tailored properties. This high-purity intermediate is essential for research and production in pharmaceutical development and agrochemical synthesis, where introducing fluorine atoms is a key strategy to modulate bioactivity, metabolic stability, and physicochemical characteristics.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery programs.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Acts as a key fluorinated component in the synthesis of advanced electronic materials for displays and lighting.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, cyclizations, and functional group transformations to create complex molecular architectures.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and the effects of fluorination in medicinal and materials chemistry.

Basic Information

Product Name	4-Fluoro-2,3-Dihydro-1H-Indene
CAS No.	57526-99-5
Molecular Formula	C9H9F
Molecular Weight	136.17 g/mol
Synonyms	4-Fluoroindane; 4-Fluoro-2,3-dihydro-1H-indene; 1H-Indene, 4-fluoro-2,3-dihydro-; 4-Fluorindan; 4-Fluoroindan; 4-Fluorinated Indane; 4-F-Indane
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-2,3-Dihydro-1H-Indene is manufactured under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.