Description

3-Chloro-3-(4-Methoxyphenyl)Acrylonitrile is a versatile and high-value organic intermediate characterized by its unique acrylonitrile structure substituted with chloro and methoxyphenyl groups. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting specific biological pathways.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural motifs can contribute to biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor in the synthesis of specialized electron-transport or host materials for display and lighting technologies.
• Liquid Crystal & Polymer Chemistry: Employed as a monomer or intermediate for creating polymers and liquid crystalline compounds with specific electronic or optical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and cyclization reactions.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex chromophores and advanced colorants for high-performance applications.

Basic Information

Product Name	3-Chloro-3-(4-Methoxyphenyl)Acrylonitrile
CAS No.	57466-68-9
Molecular Formula	C10H8ClNO
Molecular Weight	193.63 g/mol
Synonyms	(E)-3-Chloro-3-(4-methoxyphenyl)acrylonitrile; 3-Chloro-3-(p-methoxyphenyl)acrylonitrile; 2-Chloro-2-(4-methoxyphenyl)ethene-1-carbonitrile; 3-Chloro-3-(4-methoxyphenyl)-2-propenenitrile; (2E)-3-Chloro-3-(4-methoxyphenyl)prop-2-enenitrile; 4-Methoxy-β-chlorocinnamonitrile; p-Methoxy-β-chlorocinnamonitrile
EINECS	Contact for details

Quality Control

Our 3-Chloro-3-(4-Methoxyphenyl)Acrylonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.