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Diethyl(3,4-Dihydronaphthalen-1-Yloxy)Borane CAS NO 57387-79-8


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CAS No.:57387-79-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Diethyl(3,4-Dihydronaphthalen-1-Yloxy)Borane is a specialized organoboron reagent featuring a naphthalene-derived alkoxy ligand. This compound is valued for its role as a key synthetic intermediate in advanced organic transformations, particularly in cross-coupling and functionalization reactions. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: Acts as a crucial boron-based coupling partner for the synthesis of biaryl and heterobiaryl compounds, which are core structures in many active pharmaceutical ingredients (APIs).
  • Pharmaceutical Intermediate Synthesis: Serves as a building block in the multi-step synthesis of novel drug candidates, especially those containing naphthalene or tetralin scaffolds.
  • Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the introduction of specific aromatic groups is required.
  • Material Science & Organic Electronics: Employed in the synthesis of organic semiconductors, ligands for catalysts, and novel polymers with tailored electronic properties.
  • Asymmetric Synthesis & Catalysis: Can be utilized in the preparation of chiral ligands or as a reagent in stereoselective boron chemistry.

Basic Information

Product Name Diethyl(3,4-Dihydronaphthalen-1-Yloxy)Borane
CAS No. 57387-79-8
Molecular Formula C₁₄H₁₉BO
Molecular Weight 214.11 g/mol
Synonyms 1-(Diethylboryloxy)-1,2,3,4-tetrahydronaphthalene; (3,4-Dihydronaphthalen-1-yloxy)diethylborane; Diethyl((3,4-dihydro-1-naphthalenyl)oxy)borane; B-(3,4-Dihydro-1-naphthyloxy)diethylborane; Diethylboron 3,4-dihydro-1-naphtholate; Tetrahydronaphth-1-yloxy Diethylborane
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Quality Control

Our Diethyl(3,4-Dihydronaphthalen-1-Yloxy)Borane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and process development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent degradation from moisture. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or solid
Identification (IR) Conforms to structure
Assay (NMR / Titration) ≥95% (Typical 97-99%)
Purity (HPLC) ≥95%
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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