Description

(20S)-17,20,21-Tris(Trimethylsiloxy)Pregn-4-En-3-One o-Methyl Oxime is a high-purity, organosilicon-protected steroid derivative, serving as a critical advanced intermediate in complex organic synthesis. Its primary value lies in enabling precise chemical transformations for the development of novel pharmaceutical compounds and research chemicals. This compound is essential for R&D and production teams in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those focused on steroid chemistry and the synthesis of specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for investigating new synthetic pathways and structure-activity relationships in medicinal chemistry.
• Fine Chemical Synthesis: Employed in the production of high-value, specialized chemicals for advanced material science and agrochemical research.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in steroid analysis.
• Biochemical Probes: Potential use in creating molecular probes for studying steroid hormone receptors and related biological pathways.

Basic Information

Product Name	(20S)-17,20,21-Tris(Trimethylsiloxy)Pregn-4-En-3-One o-Methyl Oxime
CAS No.	57325-74-3
Molecular Formula	C30H55NO4Si3
Molecular Weight	581.99 g/mol
Synonyms	17,20,21-Tris-O-(trimethylsilyl)-pregnenolone methyl oxime; (20S)-Pregn-4-ene-3,20-dione, 17,21-bis[(trimethylsilyl)oxy]-, 3-(O-methyloxime); Tris(trimethylsiloxy)pregnenolone methyl oxime; 3-(Methoxyimino)-17,20,21-tris(trimethylsiloxy)pregn-4-ene; Pregn-4-en-3-one, 17,20,21-tris(trimethylsiloxy)-, O-methyloxime, (20S)-
EINECS	Contact for details

Quality Control

Our (20S)-17,20,21-Tris(Trimethylsiloxy)Pregn-4-En-3-One o-Methyl Oxime is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.