Description

4,5-Dihydroxy-4-(Hydroxymethyl)Cyclopentene-3-One is a versatile, high-purity cyclopentenone derivative with a unique polyhydroxylated structure. This compound serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis, enabling the construction of complex molecular architectures. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside analogs, antiviral agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, fragrances, and advanced polymer monomers.
• Academic & Industrial Research: A valuable tool in methodological development, catalysis studies, and exploring new chemical spaces in medicinal chemistry.
• Bioconjugate Chemistry: Potential use in linker chemistry for antibody-drug conjugates (ADCs) or prodrug development due to its functional handles.

Basic Information

Product Name	4,5-Dihydroxy-4-(Hydroxymethyl)Cyclopentene-3-One
CAS No.	57236-37-0
Molecular Formula	C6H8O4
Molecular Weight	144.13 g/mol
Synonyms	4-(Hydroxymethyl)-4,5-dihydroxycyclopent-2-en-1-one; 4,5-Dihydroxy-4-(hydroxymethyl)-2-cyclopenten-1-one; 4-(Hydroxymethyl)-4,5-dihydroxy-2-cyclopenten-1-one; Dihydroxy(hydroxymethyl)cyclopentenone; Cyclopentenone, 4,5-dihydroxy-4-(hydroxymethyl)-; (4R,5R)-4,5-Dihydroxy-4-(hydroxymethyl)cyclopent-2-en-1-one (for specific enantiomer)
EINECS	Contact for details

Quality Control

Our 4,5-Dihydroxy-4-(Hydroxymethyl)Cyclopentene-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis where applicable, and identity confirmation via spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (if applicable)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.