Description

1H-Imidazole, 2-Fluoro- is a fluorinated derivative of the imidazole heterocycle, serving as a critical building block in advanced organic synthesis. Its value lies in the introduction of a fluorine atom, which can dramatically alter the electronic properties, metabolic stability, and bioavailability of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used to create novel fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a functionalized backbone for creating specialized N-heterocyclic carbene (NHC) ligands and organocatalysts.
• Material Science Research: Building block for fluorinated ionic liquids, conductive polymers, and advanced organic frameworks.
• Fluorine Chemistry Studies: A valuable substrate for investigating nucleophilic aromatic substitution and other fluorinated heterocycle reactions.

Basic Information

Product Name	1H-Imidazole, 2-Fluoro-
CAS No.	57212-34-7
Molecular Formula	C3H3FN2
Molecular Weight	86.07 g/mol
Synonyms	2-Fluoroimidazole; 2-Fluoro-1H-imidazole; Fluoromidazole; 2-F-Imidazole; 2-Fluoroglyoxaline; 2-Fluoro-1H-glyoxaline; 2-Fluoromidazole
EINECS	Contact for details

Quality Control

Our 1H-Imidazole, 2-Fluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.