Description

2-Ethyl-5,5-Dimethyl-1,3,2-Dioxaborinane is a specialized organoboron compound, specifically a cyclic boronic ester, valued for its utility as a versatile synthetic intermediate and protecting group. Its primary commercial significance lies in enabling precise chemical transformations, particularly in the synthesis of complex pharmaceutical molecules and advanced materials. This chemical is essential for research and production chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity, reliable building blocks for cross-coupling reactions and other boron-mediated processes.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions for constructing biaryl and other carbon-carbon bonds in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the boronic ester moiety is crucial for introducing specific functional groups.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other advanced electronic compounds requiring precise boron integration.
• Polymer Chemistry: Employed in the synthesis of boron-containing polymers and as a modifying agent to impart specific properties to polymeric materials.
• Organic Synthesis & Protecting Group: Functions as a protecting group for diols and as a stable source of the boronic acid functionality in multi-step synthetic routes.
• Research & Development: A critical reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	2-Ethyl-5,5-Dimethyl-1,3,2-Dioxaborinane
CAS No.	57186-59-1
Molecular Formula	C7H15BO2
Molecular Weight	142.00 g/mol
Synonyms	5,5-Dimethyl-2-ethyl-1,3,2-dioxaborinane; 2-Ethyl-5,5-dimethyl-1,3,2-dioxaborinane; Ethylboronic acid 2,2-dimethyltrimethylene ester; 2,2-Dimethyltrimethylene ethylboronate; (5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)ethane; Cyclic ethylboronic ester with neopentyl glycol
EINECS	Contact for details

Quality Control

Our 2-Ethyl-5,5-Dimethyl-1,3,2-Dioxaborinane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing including GC, NMR, and HPLC analysis to verify identity, assay, and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring stringent material standards, including cGMP environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.