Description

4-Acridinecarboxylic Acid, 9,10-Dihydro-6-(Trifluoromethyl)- is a specialized heterocyclic carboxylic acid derivative of acridine, distinguished by the presence of a trifluoromethyl group. This compound is a high-value synthetic intermediate prized for its unique electronic and steric properties imparted by the fluorine atoms. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting CNS and anti-infective applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel acridine-based drug candidates, including potential antitumor, antimicrobial, and central nervous system (CNS) agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a starting material for creating functional dyes, fluorescent probes, and organic electronic materials due to the acridine core's photophysical properties.
• Chemical Biology Tool: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: Essential for fundamental organic synthesis research and discovery projects in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-Acridinecarboxylic Acid, 9,10-Dihydro-6-(Trifluoromethyl)-
CAS No.	57100-31-9
Molecular Formula	C15H10F3NO2
Molecular Weight	293.24 g/mol
Synonyms	9,10-Dihydro-6-(trifluoromethyl)acridine-4-carboxylic acid; 6-(Trifluoromethyl)-9,10-dihydroacridine-4-carboxylic acid; 4-Carboxy-6-trifluoromethyl-9,10-dihydroacridine; Dihydro-6-trifluoromethylacridine-4-carboxylic acid; 9,10-Dihydro-6-(trifluoromethyl)-4-acridinecarboxylic acid
EINECS	Contact for details

Quality Control

We supply 4-Acridinecarboxylic Acid, 9,10-Dihydro-6-(Trifluoromethyl)- in high-purity grades suitable for research and advanced synthesis. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.