Description

3-Bromo-1-(4-Fluorophenyl)Propan-1-One is a versatile and high-purity organic building block essential for advanced chemical synthesis. Its molecular structure, featuring both bromo and fluoro substituents, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers where specific halogenated aromatic ketones are required.
• Custom Synthesis and Contract Manufacturing: An important building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and R&D Laboratories: Utilized in medicinal chemistry programs and organic synthesis research for method development and creating compound libraries.

Basic Information

Product Name	3-Bromo-1-(4-Fluorophenyl)Propan-1-One
CAS No.	57056-43-6
Molecular Formula	C9H8BrFO
Molecular Weight	231.06 g/mol
Synonyms	3-Bromo-1-(4-fluorophenyl)-1-propanone; 1-Propanone, 3-bromo-1-(4-fluorophenyl)-; 4-Fluorophenacyl bromide; ω-Bromo-4-fluoroacetophenone; 3-Bromo-1-(p-fluorophenyl)propan-1-one; p-Fluorophenacyl bromide; 4'-Fluorophenacyl bromide; 3-Bromo-4'-fluoropropiophenone
EINECS	Contact for details

Quality Control

Our 3-Bromo-1-(4-Fluorophenyl)Propan-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.